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Episode TimeStamps:
00:00 - Introduction to George Patterson and his journey from physics to quantitative investing
03:12 - Why multidisciplinary teams matter in modern quant investing
04:13 - Inside PGIM Quant Solutions and the evolution of multi asset investing
06:03 - How markets and macro investing have changed since the 1990s
09:12 - The future of the 60/40 portfolio and institutional portfolio construction
12:11 - Private markets, liquidity challenges and institutional investor concerns
13:25 - Inflation, commodities and building modern inflation hedges
19:33 - Detecting macro regimes using quantitative models
23:26 - The hardest part of systematic investing: trusting the process
27:00 - Covid, model failures and managing regime shifts in real time
30:07 - Portfolio protection, options strategies and volatility overlays
32:01 - How AI and large language models are transforming quantitative research
40:02 - Fiscal risks, inflation concerns and the changing rate environment
44:26 - Simplicity versus complexity in quantitative model design
48:05 - Why markets evolve faster today and how models must adapt
51:08 - Retail investors, meme stocks and market distortions
53:33 - Emerging markets and where long term opportunities may exist
55:08 - The future of quant investing and the limits of AI hype
57:10 - George Patterson’s career advice for aspiring quants

